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Think you have
a mind for schiziphrenia?
Click to begin
About how many adults suffer from schizophrenia worldwide?
A1,000,000
There are approximately 26,000,000 adults with schizophrenia world wide!
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B2,600,000
There are approximately 26,000,000 adults with schizophrenia world wide!
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C10,000,000
There are approximately 26,000,000 adults with schizophrenia world wide!
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D26,000,000
There are approximately 26,000,000 adults with schizophrenia world wide!
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I’m not sure
There are approximately 26,000,000 adults with schizophrenia world wide!
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At any given time, roughly what proportion of people with schizophrenia are experiencing negative symptoms?
A20%
Nearly 60% of patients with schizophrenia my experience negative symptoms at any given time!
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B40%
Nearly 60% of patients with schizophrenia my experience negative symptoms at any given time!
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C60%
Nearly 60% of patient’ with schizophrenia my experience negative symptoms at any given time!
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D80%
Nearly 60% of patient’ with schizophrenia my experience negative symptoms at any given time!
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I’m not sure
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The severity of negative symptoms is a major indicator of poor outcomes in patients with schizophrenia. True or false?
True
The severity of negative symptoms is predictive of poor outcomes and limit a patient’s chance of recovery.
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False
the severity of negative symptoms is predictive of poor outcomes and limit a patient’s chance of recovery.
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I’m not sure
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NMDA receptors are expressed in areas of the brain involving which of the following functions.
ANMDA receptors may mediate the release of neurotransmiters.
NMDA receptors can be found in regions of the brain involving motivation, goal-directed behavior, and emotions. These receptors are widely expressed in the brain in such areas as the prefrontal cortex, hippocampus, auditory cortex, and visual cortex.
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BGoal-directed behavior
NMDA receptors can be found in regions of the brain involving motivation, goal-directed behavior, and emotions. These receptors are widely expressed in the brain in such areas as the prefrontal cortex, hippocampus, auditory cortex, and visual cortex.
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CEmotions
NMDA receptors can be found in regions of the brain involving motivation, goal-directed behavior, and emotions. These receptors are widely expressed in the brain in such areas as the prefrontal cortex, hippocampus, auditory cortex, and visual cortex.
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DAll of the above
NMDA receptors can be found in regions of the brain involving motivation, goal-directed behavior, and emotions. These receptors are widely expressed in the brain in such areas as the prefrontal cortex, hippocampus, auditory cortex, and visual cortex.
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I’m not sure
NMDA receptors can be found in regions of the brain involving motivation, goal-directed behavior, and emotions. These receptors are widely expressed in the brain in such areas as the prefrontal cortex, hippocampus, auditory cortex, and visual cortex.
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The NMDA receptor may play a key role in the pathophysiology of schizophrenia, because:
ANMDA receptors may mediate the release of neurotransmiters.
NMDA receptors can be found in regions of the brain involving motivation, goal-directed behavior, and emotions. These receptors are widely expressed in the brain in such areas as the prefrontal cortex, hippocampus, auditory cortex, and visual cortex.
Sed ac urna sapien. Maecenas erat dui, rhoncus id egestas sed, faucibus quis odio? Nullam nec lectus nec dui facilisis iaculis. Nunc tristique congue lorem in ultricies! Proin felis erat, tristique elementum consectetur ut; euismod eget enim.
BNMDA receptors may be a common pathy way of symptoms.
NMDA receptors can be found in regions of the brain involving motivation, goal-directed behavior, and emotions. These receptors are widely expressed in the brain in such areas as the prefrontal cortex, hippocampus, auditory cortex, and visual cortex.
Sed ac urna sapien. Maecenas erat dui, rhoncus id egestas sed, faucibus quis odio? Nullam nec lectus nec dui facilisis iaculis. Nunc tristique congue lorem in ultricies! Proin felis erat, tristique elementum consectetur ut; euismod eget enim.
CEmotions
NMDA receptors can be found in regions of the brain involving motivation, goal-directed behavior, and emotions. These receptors are widely expressed in the brain in such areas as the prefrontal cortex, hippocampus, auditory cortex, and visual cortex.
Sed ac urna sapien. Maecenas erat dui, rhoncus id egestas sed, faucibus quis odio? Nullam nec lectus nec dui facilisis iaculis. Nunc tristique congue lorem in ultricies! Proin felis erat, tristique elementum consectetur ut; euismod eget enim.
DAll of the above
NMDA receptors can be found in regions of the brain involving motivation, goal-directed behavior, and emotions. These receptors are widely expressed in the brain in such areas as the prefrontal cortex, hippocampus, auditory cortex, and visual cortex.
Sed ac urna sapien. Maecenas erat dui, rhoncus id egestas sed, faucibus quis odio? Nullam nec lectus nec dui facilisis iaculis. Nunc tristique congue lorem in ultricies! Proin felis erat, tristique elementum consectetur ut; euismod eget enim.
I’m not sure
NMDA receptors can be found in regions of the brain involving motivation, goal-directed behavior, and emotions. These receptors are widely expressed in the brain in such areas as the prefrontal cortex, hippocampus, auditory cortex, and visual cortex.
Sed ac urna sapien. Maecenas erat dui, rhoncus id egestas sed, faucibus quis odio? Nullam nec lectus nec dui facilisis iaculis. Nunc tristique congue lorem in ultricies! Proin felis erat, tristique elementum consectetur ut; euismod eget enim.
NMDA receptors can mediate the downstream release of which of the following neurotransmitters:
AGlutamate
NMDA receptors can mediate the downstram release of neurotransmitters such as glutamate, dopamine, and GABA, which are thought the be dysregulated in schiziphrenia. Glutamate and dopamine have excitatory effects on surrounding neurons and GABA has inhibitory effects.
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BGABA
NMDA receptors can mediate the downstram release of neurotransmitters such as glutamate, dopamine, and GABA, which are thought the be dysregulated in schiziphrenia. Glutamate and dopamine have excitatory effects on surrounding neurons and GABA has inhibitory effects.
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CDopamine
NMDA receptors can mediate the downstram release of neurotransmitters such as glutamate, dopamine, and GABA, which are thought the be dysregulated in schiziphrenia. Glutamate and dopamine have excitatory effects on surrounding neurons and GABA has inhibitory effects.
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DAll of the above
NMDA receptors can mediate the downstram release of neurotransmitters such as glutamate, dopamine, and GABA, which are thought the be dysregulated in schiziphrenia. Glutamate and dopamine have excitatory effects on surrounding neurons and GABA has inhibitory effects.
Sed ac urna sapien. Maecenas erat dui, rhoncus id egestas sed, faucibus quis odio? Nullam nec lectus nec dui facilisis iaculis. Nunc tristique congue lorem in ultricies! Proin felis erat, tristique elementum consectetur ut; euismod eget enim.
I’m not sure
NMDA receptors can mediate the downstram release of neurotransmitters such as glutamate, dopamine, and GABA, which are thought the be dysregulated in schiziphrenia. Glutamate and dopamine have excitatory effects on surrounding neurons and GABA has inhibitory effects.
Sed ac urna sapien. Maecenas erat dui, rhoncus id egestas sed, faucibus quis odio? Nullam nec lectus nec dui facilisis iaculis. Nunc tristique congue lorem in ultricies! Proin felis erat, tristique elementum consectetur ut; euismod eget enim.
The possible role of NMDA receptor hypofunction was revealed more than 20 years ago, with the observation that clinical use of certain dissociative anesthetics such as phycyclidine (PCP) had corresponding side effects resembling which symptoms of schizophrenia?
APositive
Studies showed that healthy subjects given NMDA receptor antagonists such as PCP and ketamine (a PCP derivative) developed a clinical picture resembling schizophrenia, including positive and negative symptoms and cognitive deficits.
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BNegative
Studies showed that healthy subjects given NMDA receptor antagonists such as PCP and ketamine (a PCP derivative) developed a clinical picture resembling schizophrenia, including positive and negative symptoms and cognitive deficits.
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CCognitive
Studies showed that healthy subjects given NMDA receptor antagonists such as PCP and ketamine (a PCP derivative) developed a clinical picture resembling schizophrenia, including positive and negative symptoms and cognitive deficits.
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DAll of the above
Studies showed that healthy subjects given NMDA receptor antagonists such as PCP and ketamine (a PCP derivative) developed a clinical picture resembling schizophrenia, including positive and negative symptoms and cognitive deficits.
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I’m not sure
Studies showed that healthy subjects given NMDA receptor antagonists such as PCP and ketamine (a PCP derivative) developed a clinical picture resembling schizophrenia, including positive and negative symptoms and cognitive deficits.
Sed ac urna sapien. Maecenas erat dui, rhoncus id egestas sed, faucibus quis odio? Nullam nec lectus nec dui facilisis iaculis. Nunc tristique congue lorem in ultricies! Proin felis erat, tristique elementum consectetur ut; euismod eget enim.
One potential method of improving NMDA receptor function is to increase the synaptic level of which amino acid?
AGlycine
Increasing synaptic levels of glycine may enhance NMDA receptor function.
Glycine is a naturally occuring amino acid. It can act as either a neurotransmitter or a building block for proteins.
BSerine
Increasing synaptic levels of glycine may enhance NMDA receptor function.
Glycine is a naturally occuring amino acid. It can act as either a neurotransmitter or a building block for proteins.
CGlutamic acid
Increasing synaptic levels of glycine may enhance NMDA receptor function.
Glycine is a naturally occuring amino acid. It can act as either a neurotransmitter or a building block for proteins.
DLysine
Increasing synaptic levels of glycine may enhance NMDA receptor function.
Glycine is a naturally occuring amino acid. It can act as either a neurotransmitter or a building block for proteins.
I’m not sure
Increasing synaptic levels of glycine may enhance NMDA receptor function.
Glycine is a naturally occuring amino acid. It can act as either a neurotransmitter or a building block for proteins.
Glycine levels in the synapse may be regulated by glycine transporter type 1(GlyT-1), which are located where?
APre-synapse
Glycine transporter 1(GlyT-1) is located on glial cells that surround synapses with NMDA receptors.
Glyt-1 tightly regulates and maintains synaptic glycine concentrations by acting as a reuptake pump.
BPost-synapse
Glycine transporter 1(GlyT-1) is located on glial cells that surround synapses with NMDA receptors.
Glyt-1 tightly regulates and maintains synaptic glycine concentrations by acting as a reuptake pump.
CGlial Cells
Glycine transporter 1(GlyT-1) is located on glial cells that surround synapses with NMDA receptors.
Glyt-1 tightly regulates and maintains synaptic glycine concentrations by acting as a reuptake pump.
DAll of the above
Glycine transporter 1(GlyT-1) is located on glial cells that surround synapses with NMDA receptors.
Glyt-1 tightly regulates and maintains synaptic glycine concentrations by acting as a reuptake pump.
I’m not sure
Studies showed that healthy subjects given NMDA receptor antagonists such as PCP and ketamine (a PCP derivative) developed a clinical picture resembling schizophrenia, including positive and negative symptoms and cognitive deficits.
Sed ac urna sapien. Maecenas erat dui, rhoncus id egestas sed, faucibus quis odio? Nullam nec lectus nec dui facilisis iaculis. Nunc tristique congue lorem in ultricies! Proin felis erat, tristique elementum consectetur ut; euismod eget enim.
Which co-agonists are needed to activate NMDA receptors?
AGlutamate and serine
The NMDA receptor is an ion channel that can only be activated and opened when it binds both glutamate and glycine.
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BGlycine and dopamine
The NMDA receptor is an ion channel that can only be activated and opened when it binds both glutamate and glycine.
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CGlutamate and dopamine
The NMDA receptor is an ion channel that can only be activated and opened when it binds both glutamate and glycine.
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DGlutamate and glycine
The NMDA receptor is an ion channel that can only be activated and opened when it binds both glutamate and glycine.
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I’m not sure
The NMDA receptor is an ion channel that can only be activated and opened when it binds both glutamate and glycine.
Sed ac urna sapien. Maecenas erat dui, rhoncus id egestas sed, faucibus quis odio? Nullam nec lectus nec dui facilisis iaculis. Nunc tristique congue lorem in ultricies! Proin felis erat, tristique elementum consectetur ut; euismod eget enim.